Fruit Fly Brain Research Published in Neurotoxicology

Boz Institute is proud to announce the publication of a new paper, Locomotion and brain gene expression exhibit sex-specific non-monotonic dose-response to HFPO-DA during Drosophila melanogaster lifespan. The paper was published in Neurotoxicology, volume 96, and examines the potential sex-specific stress responses to a new chemical (HFPO-DA) used in manufacturing processes on populations of fruit flies. Due to the public health concern of prior chemicals (PFAS) used in manufacturing, this paper aims to uncover the potential effects this replacement chemical (HFPO-DA) has on the brain, behavior and lifespan.

To read this publication and others from Boz, click HERE.

Four Masters in Four Weeks

Within a span of four weeks in Spring 2022, four Boz researchers completed their Master of Science programs:

  1. Armando Vazquez – UCSD M.S. / B.S.; Thesis Title: “A network approach to investigating the role of the Sorghum bicolor transcription factor SbWRKY86 in promoting plant resistance to aphids”
  1. Sylvia Gong – SDSU Graduate School of Public Health; Thesis Title: “Acute GenX exposure induces spinal deformations and arrhythmia, and alters expression of genes involved in cardiac, vascular, neural, and visual systems during zebrafish (Danio rerio) early development”
  1. Zuying Feng – SDSU Graduate School of Public Health; Thesis Title: “Physiological and Transcriptomic Effects of Hexafluoropropylene Oxide Dimer Acid (GenX) in Caenorhabditis elegans during Early Development”
  1. Jeanne Vu – SDSU Graduate School of Public Health; Thesis Title: “Locomotor ability and brain gene expression in Drosophila melanogaster exhibit non-monotonic dose-response to HFPO-DA”

We are immensely proud of their efforts and accomplishments and look forward to their continued research endeavors at Boz (Armando and Zuying) and learning about their new science and technology adventures (Sylvia – currently at Cardinal Biocraft and Jeanne – currently at Meta).