Molecular Phylogenetics Program Research Immersion Program – HYBRID

Hybrid 11-week program: September 27 – December 9, 2021

This hybrid research-immersion course utilizes marine invertebrates (abalone, purple sea urchins, bay mussels), vertebrates (salt-tolerant fish – Japanese medaka, zebrafish), insects – fruit flies, and nematode – worms – to genetically barcode (sequence) the mitochondrial cytochrome C-oxidase and perform a phylogenetics analysis. Students will learn evolutionary and molecular biology concepts, extract DNA from multiple species and PCR-amplify a genetic marker to analyze mutation rates, sequence relatedness/speciation, and comparative sequencing analysis of a metabolic gene critical for adaptive metabolic mechanisms. The course content is a mix of evolutionary biology theory and modeling, standard and advanced molecular biology techniques, and bioinformatics analysis. Part of the course complements the ongoing research project in partnership with National Park Service, which utilizes environmental DNA (eDNA) methodology to better understand the adaptive mechanisms and responses to environmental stressors of Southern California endangered black abalone population. During the 11-weeks hybrid course meting twice weekly, students will perform research in-person once per week, and meet virtually to discuss concepts and primary scientific literature, design experiment, analyze the data, etc. once per week. The course will conclude with the science seminar during which students will present their research in-person to a selected audience.

Course is available for 4 pre-college units.

Course Delivery: Hybrid

Grade Level: Students must currently be in 10th–12th grade

Academic Schedule: 

  • 11-week program, September 27 – December 9, 2021
  • Choose from one of two sessions
    • Mon (virtual) and Wed (in person lab day), 4:00 – 6:00 PM PST
    • Tue (virtual) and Thu (in person lab day), 4:00-6:00 PM PST
  • Synchronous online teaching a week
  • 4 hours of work required outside of online lecture/lab a week

Scholarship Opportunities: Limited number available

To be notified of future sessions programming: email info@bozinstitute.org

The Boz research immersion program will be online for the foreseeable future.  Our scientists are looking forward to getting students back in the lab, but for now our top priority is safety.

Introduction to Biostatistics and Bioinformatics Program – ONLINE (part of UCSD Extension Futures Program)

Online 11-week program: September 27 – December 8, 2021

This course utilizes two different case studies/data sets to introduce students to experimental design, biostatistics fundamentals, management of a large gene expression data set, and basics bioinformatics concepts. Data sets include environmental assays performed on developing invertebrate embryos and RNA Sequencing gene expression data from animal physiology/aging project. Concepts covered during the first part of the course cover experimental design, biological and technical replicates and statistical power, central limit theorem and Bayes rules/theorem, 1-way Analysis of Variance (ANOVA) and pairwise comparison t-test. Second part of the course focuses on differential gene expression workflow, data normalization, principal component analysis (PCA), and introduction to Bioinformatics databases (GenBank, UCSC genome browser, David Bioinformatics, STRING) utilizing RNA Seq analysis (sequence alignments, gene finding, and differential gene expression analysis).

Course is available for 4 pre-college units.

Course Delivery: Live Online

Grade Level: Students must currently be in 10th–12th grade

Academic Schedule: 

  • 11-week program: July 6 – August 12, 2021
  • Mondays and Wednesdays 3:00 – 4:20 PM PST
  • Synchronous online teaching a week
  • 4 hours of work required outside of online lecture/lab a week

Scholarship Opportunities: Limited number available

To be notified of future session programming: email info@bozinstitute.org