Genes Under Stress

The climate change environmental stressors can compromise lifespan, immunity, and have acute and chronic adverse systemic effects on individuals and populations. We challenge fruit flies with high temperature and UV radiation while worsening their air quality and restricting caloric intake to quantify their stress response. As female and male sensitivities may differ, we study sex-specific multigenerational effects to identify physiological and hereditary stress-induced phenotypes. We focus on multigenerational epigenetic effects on brain gene expression in fruit fly model organism and natural populations.

*For more information about this project please contact: info@bozinstitute.org

Investigator

Lindsey Griffin

John Kim

Jenna Jedlicki